KEY TAKEAWAYS

• Synthesized in the 1950s by Dr. Paul Janssen.

• Introduced in the 1960s as an intravenous anesthetic under the brand name Sublimaze.

• Fentanyl is approximately 50 to 100 times more potent than morphine.

FENTANYL DRUGS INCREASES 62%

Daniel TJ International Reporter Tokyo, Japan

In the mid-20th century, during the search for new medications, Dr. Paul Janssen, a distinguished Belgian chemist, unveiled a breakthrough compound: Fentanyl.

Developed under the Pharmaceutical Company: Janssen Pharmaceutica, this synthetic opioid emerged as a promising solution to alleviate pain.

Introduced in the 1960s as Sublimaze, an intravenous anesthetic, Fentanyl swiftly gained acclaim for its unparalleled potency and rapid onset of action.

Its ability to induce anesthesia and manage pain during surgeries revolutionized medical practice, earning it a revered status in hospitals worldwide.

As demand for effective pain management escalated, pharmaceutical giants capitalized on Fentanyl's potential, birthing a diverse array of formulations tailored to specific needs.

From transdermal patches to nasal sprays, each variant aimed to provide swift relief in diverse clinical scenarios.

However, as a great therapeutic tool, lies another reality: Fentanyl's potency, surpassing morphine by 50 to 100 times, renders it a double-edged sword.

While invaluable for managing excruciating pain, its potency makes it highly susceptible to misuse and abuse.

Where is Fentanyl coming from?

According to the DEA Intelligence Program in the United States, China remains the primary source of fentanyl. Fentanyl is distributed from China to Mexico, and then into America.

Some succumbed to its powerful euphoric effects, while others unwittingly ingested it, laced into illicit drugs like heroin or counterfeit pills.

The misuse of Fentanyl dramatically increased the risk of fatal overdose, as victims were often unaware of the potency lurking within.

In response to the crisis, public health officials and law enforcement agencies mobilized, implementing a multifaceted approach.

STRATEGIES TO STOP FENTANYL

Strategies ranged from expanding access to naloxone, a life-saving opioid overdose reversal medication, to intensifying drug education and prevention initiatives, and imposing stringent regulations to curb illicit production and distribution.

However, despite these concerted efforts, the fentanyl conundrum persists, exacerbated by the emergence of new analogs and synthetic variations.

These compounds, with their unpredictable potencies and pharmacological effects, pose a formidable challenge to containment efforts, perpetuating the cycle of tragedy.

Today, as Fentanyl retains its indispensable role in pain management, stakeholders grapple with a vexing dilemma: how to harness its therapeutic benefits while mitigating the perils of diversion and misuse.

Fentanyl continues to flow from China and Mexico while the amount of the deadly drug is increasing in America. Between 2022 and 2023 there has been a whopping 62% increase of fentanyl into the USA.

The DEA reported that the fentanyl crises is the deadliest drug that America has ever experienced. In term of deaths, fentanyl kills 200 people per day.

The border between America and Mexico [is not] controlled by America

To be clear, the drug fentanyl is able to be distributed into America because the border between America and Mexico is not controlled by America. The border is controlled by the Cartels in Mexico.

Why? Because America reacts to what the Cartels have planned to get the drugs into America. America is always reacting. Not stopping fentanyl from flowing into America.

And one more point to make, a Mexican Security Official assisted the Cartels to distribute fentanyl into The United States by offering bribes to look the other way

The Cartels in Mexico make billions of dollars at the expense of Americans.

So why are Americans taking fentanyl in the first place?

There are many reasons why Americans take fentanyl. Some do not know what fentanyl is while others take other kinds of drugs that are not fatal, however unbeknownst to them, the non-lethal drug is laced with the deadly fentanyl.

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